Gestational diabetes & diabetes in pregnancy

The incidence and risk factors of postpartum diabetes in women from Bangladesh, India and Sri Lanka (South Asia) with prior gestational diabetes mellitus: Results from the LIVING study

Diabetes Res Clin PractPublished Cohort study within a randomised controlled trial

Authors' conclusion

A high incidence of DM was found in women with prior GDM in South Asia, with significant variation between countries. Women from Bangladesh had a significantly higher pregnancy count, family history of DM and overweight/obese status, despite having significantly lower age, which could be responsible for their higher rates of DM.

Study context

Population
Women with prior gestational diabetes mellitus (GDM) (IADPSG criteria) from Bangladesh, India and Sri Lanka, with postpartum oral glucose tolerance test (OGTT); mean ± SD age 31.0 ± 5.0 years
Participants
1,808 women
Comparison
Bangladesh vs Sri Lanka vs India
Primary endpoint
Incident DM (glycaemic category from OGTT, ADA criteria)
Follow-up
Median 1.82 years after childbirth
Methodological detailsLIVING study, multicentre, 19 centres in Bangladesh, India and Sri Lanka
  • LIVING study
  • Multicentre
  • 19 centres in Bangladesh, India and Sri Lanka

Primary result

As reported in the abstract

Incident DM · between childbirth and last follow-up; median 1.82 years

Incident DM, women

310

17.1 %

Incidence

10.75/100 person years

Further findings

OutcomeBangladeshSri LankaIndia
Cumulative incidence of DM by country16.49/100 person years12.74/100 person years7.21/100 person years

Cumulative incidence of DM by country

Higher in Bangladesh than in Sri Lanka and India

Risk factors for incident DM

Higher age, lower education, higher prior pregnancy count, prior GDM, family history of DM and postpartum overweight/obese status were significantly associated with incident DM

Original publication

The incidence and risk factors of postpartum diabetes in women from Bangladesh, India and Sri Lanka (South Asia) with prior gestational diabetes mellitus: Results from the LIVING study. Diabetes Res Clin Pract. Published 31 August 2023. doi:10.1016/j.diabres.2023.110893

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