Gestational diabetes & diabetes in pregnancy
Pancreatic-derived factor predicts remission of impaired glucose tolerance women with history of gestational diabetes
Authors' conclusion
Circulating PANDER concentration is inversely associated with the remission of IGT in women with GMD history at one year postpartum.
Study context
- Population
- Women with impaired glucose tolerance (IGT) and history of gestational diabetes mellitus (GDM), enrolled 4–12 weeks postpartum, receiving lifestyle intervention
- Participants
- 113 women
- Exposure
- High and very high vs low PANDER level
- Outcome
- Remission of IGT (return to normal glucose tolerance)
- Follow-up
- One year postpartum
Main finding
As reported in the abstract
Remission of IGT
Returned to normal glucose tolerance (all subjects)
48.7%
55/113
AUC of PANDER level for remission of IGT
0.702
95% CI 0.595–0.809
AUC of PANDER combined with clinical information
0.812
95% CI 0.725–0.899P < 0.001
Observational data: associations, not effects.
Original publication
Pancreatic-derived factor predicts remission of impaired glucose tolerance women with history of gestational diabetes. Diabetes Res Clin Pract. Published 30 August 2023. doi:10.
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