Gestational diabetes & diabetes in pregnancy
Association between obesity at age 20 and postpartum glucose tolerance in women with a history of gestational diabetes mellitus
Main finding · Onset of postpartum IGT and DMResult — go to the resultAdjusted relative risk 1.726 95 % CI 1.217–2.446Authors' conclusion
Japanese women need to maintain a normal weight from age 20 to prevent the onset of DM.
Study context
- Population
- Women with gestational diabetes mellitus (GDM) who underwent prenatal glycemic control and a 75-g OGTT 6 to 12 weeks after delivery
- Participants
- 433 women
- Exposure
- Obesity at age 20 vs no obesity at age 20
- Outcome
- Postpartum glucose tolerance (onset of postpartum impaired glucose tolerance (IGT) and diabetes mellitus (DM); postpartum insulin resistance)
- Follow-up
- 6 to 12 weeks after delivery
Methodological detailsmultivariable Poisson regression with robust variance
- Multivariable Poisson regression with robust variance
Main finding
Onset of postpartum IGT and DM
Adjusted relative risk
1.726
95 % CI 1.217–2.446
Obesity at age 20vs No obesity at age 20
aRR 1.726 (95 % CI 1.217–2.446)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aRR (95 % CI) | |
|---|---|---|
| Postpartum insulin resistance · 6 to 12 weeks after deliveryIndependent predictor | 1.532 (1.085–2.164) | |
| Onset of postpartum IGT and DM: obesity at age 20, pre-pregnancy and postpartumvs no history of obesity · 6 to 12 weeks after delivery | 2.104 (1.390–3.185) | |
| 0.20.5125Adjusted relative risk (log scale) |
Postpartum insulin resistance by weight gain from age 20 to pregnancy · 6 to 12 weeks after delivery
- Weight gain from age 20 to pregnancy, adjusted risk ratios (aRR)
- 1.050 (95 % CI 1.024-1.077)
- Independent predictor
Original publication
Association between obesity at age 20 and postpartum glucose tolerance in women with a history of gestational diabetes mellitus. Diabetes Res Clin Pract. Published 3 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →