Implementation of fully closed‐loop insulin delivery for inpatients with diabetes: Real‐world outcomes
Authors' conclusion
We have demonstrated that the fully closed-loop system can be safely and effectively implemented by a diabetes outreach team in complex medical and surgical inpatients with challenging glycaemic control.
Study context
- Population
- Inpatients with diabetes on medical and surgical wards, large teaching hospital in Cambridge, UK; prioritised those with more challenging diabetes management; mean ± SD age 61 ± 16 years, 8 females, 24 males555 closed-loop days
- Participants
- 32 inpatients
- Outcome
- Glycaemic control during closed-loop use
- Follow-up
- 12 months since implementation
Methodological detailssingle-centre, real-world, Multimodal staff training (face-to-face workshops, online modules, standard operating procedures); set-up and maintenance by inpatient diabetes team; multidisciplinary patient selection
- Single-centre
- Real-world
- Multimodal staff training (face-to-face workshops, online modules, standard operating procedures); set-up and maintenance by inpatient diabetes team; multidisciplinary patient selection
Main finding
As reported in the abstract
- TIR 3.9-10.0 mmol/L
- 53.3 ± 18.3%
- Mean glucose
- 10.7 ± 1.9 mmol/L
- Time with glucose >10.0 mmol/L
- 46.0 ± 18.2%
- Time with sensor glucose below 3.9 mmol/L, median [IQR]
- 0.38 [0.00, 0.85]
- Closed-loop days per inpatient, median [IQR]
- 14 [6, 22] days
Safety
Severe hypoglycaemia or DKA during closed-loop use
- Episodes of severe hypoglycaemia or DKA
- 0
Original publication
Implementation of fully closed‐loop insulin delivery for inpatients with diabetes: Real‐world outcomes. Diabet Med. Published 28 March 2023. doi:10.
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