Glycaemia and cardiac arrhythmias in people with type 1 diabetes: A prospective observational study
Authors' conclusion
Acute hypoglycaemia and hyperglycaemia during daytime may increase the risk of arrhythmias in individuals with type 1 diabetes. However, no such associations were found during night-time, indicating diurnal differences in arrhythmia susceptibility.
Study context
- Population
- Adults with T1D
- Participants
- 30 adults
- Exposure
- Hypoglycaemia, hyperglycaemia and glycaemic variability vs euglycaemia
- Outcome
- Daytime and night-time incident rate ratios (IRRs) of arrhythmias
- Follow-up
- 12 months
Methodological detailsexploratory, 12-month
- Exploratory
- 12-month
Main finding
As reported in the abstract
Arrhythmia risk
Each group vs euglycaemiaEstimate (95% CI)
Hypoglycaemiadaytime; trend
IRR per 5 minutes in hypoglycaemia 1.08(0.99–1.18)
Hyperglycaemiadaytime
IRR, occurrence of hyperglycaemia 2.03(1.21–3.40)
Hyperglycaemiadaytime
IRR per 5 minutes in hyperglycaemia 1.07(1.02–1.13)
Observational data: associations, not effects.
Further findings
Glycaemic variability (SD and CV) and arrhythmia risk
- Increased glycaemic variability not associated with increased arrhythmia risk during daytime; reduced risk during night-time
Original publication
Glycaemia and cardiac arrhythmias in people with type 1 diabetes: A prospective observational study. Diabetes Obes Metab. Published 18 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →