Global, regional and national burdens of chronic kidney disease due to T1DM and T2DM among adolescents and young adults aged 10–35 years from 1990–2021: A trend analysis based on the global burden of disease study 2021
Authors' conclusion
The burden of CKD-T1D and CKD-T2D showed a pandemic-related shift. Middle-SDI countries face high incidence and mortality, while high-SDI countries report lower mortality but higher prevalence. Public health interventions are especially needed in low and middle-SDI countries and island nations.
Study context
- Population
- Adolescents and young adults aged 10–35 years with chronic kidney disease (CKD) due to T1D (CKD-T1D) or T2D (CKD-T2D), global, regional and national levels, 1990–2021
- Outcome
- Trends in CKD-T1D and CKD-T2D incidence, prevalence, mortality and DALYs
- Follow-up
- 1990–2021
Methodological detailsjoinpoint regression analysis, decomposition analysis
- Joinpoint regression analysis
- Decomposition analysis
Main finding
As reported in the abstract
- Globally, CKD-T1D incidence rose until 2019, then declined
- CKD-T2D incidence declined initially, then increased after 2019
- Males generally had higher values of all indicators, except CKD-T1D prevalence, higher in females
- Central Latin America had the largest mortality increase; Oceania had the highest mortality rates
- Oceania countries had the highest disability-adjusted life years (DALYs) for both CKD types in 2021
Original publication
Global, regional and national burdens of chronic kidney disease due to T1DM and T2DM among adolescents and young adults aged 10–35 years from 1990–2021: A trend analysis based on the global burden of disease study 2021. Diabetes Res Clin Pract. Published 3 January 2025. doi:10.
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