Gestational diabetes & diabetes in pregnancy
Gestational diabetes mellitus and its impact on maternal and neonatal outcomes in Indigenous populations: a systematic review and meta-analysis
Authors' conclusion
These findings show that Indigenous women with GDM are at greater risk of perinatal complications than those without GDM.
Study context
- Population
- Indigenous populations globally; studies from Canada, the United States and Australia20 studies
- Comparison
- Gestational diabetes mellitus (GDM) vs no GDM
- Outcome
- Adverse maternal and neonatal pregnancy outcomes
Methodological detailsrandom-effects model, quality assessed with Newcastle-Ottawa Scale and CONSIDER Statement, 4 studies had low or medium risk of bias, Only 25% of studies reported Indigenous involvement in the research process
- Random-effects model
- Quality assessed with Newcastle-Ottawa Scale and CONSIDER Statement
- 4 studies had low or medium risk of bias
- Only 25% of studies reported Indigenous involvement in the research process
Pooled result
As reported in the abstract
Adverse pregnancy outcomes
Each group vs no GDMEstimate (95% CI)
GDM
RR, caesarean section 1.83(1.63–2.06)
GDM
RR, shoulder dystocia 3.21(2.94–3.50)
GDM
RR, large for gestational age 2.35(1.46–3.77)
GDM
RR, macrosomia 1.75(1.48–2.07)
GDM
RR, preterm birth 1.36(1.09–1.69)
GDM
RR, hypoglycaemia 8.17(4.39–15.22)
GDM
RR, low birth weight 0.80(0.69–0.91)
GDM
RR, small for gestational age 0.44(0.39–0.50)
Original publication
Gestational diabetes mellitus and its impact on maternal and neonatal outcomes in Indigenous populations: a systematic review and meta-analysis. Diabetes Res Clin Pract. Published 12 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →