Gestational diabetes & diabetes in pregnancy
Time restricted eating and exercise training before and during pregnancy for people with increased risk of gestational diabetes: single centre randomised controlled trial (BEFORE THE BEGINNING)
Primary result · 2-h plasma glucose in OGTTResult — go to the resultMean difference 0.48 mmol/L 95% CI −0.05 to 1.01Authors' conclusion
A combination of time restricted eating and exercise training started before and continued throughout pregnancy had no significant effect on glycaemic control in late pregnancy.
Study context
- Population
- People contemplating pregnancy with ≥1 risk factor for GDM; university hospital, Trondheim, Norway111 became pregnant
- Participants
- 167 people
- Comparison
- Prepregnancy lifestyle intervention vs standard care
- Interventionn = 84
- Controln = 83reference
- Primary endpoint
- 2-hour plasma glucose in OGTT
- Follow-up
- Gestational week 28
Methodological detailssingle-centre, Enrolled 2 October 2020 to 12 May 2023, 1 intervention participant excluded (prepregnancy diabetes); pregnancy data of 1 control participant excluded (twin pregnancy)
- Single-centre
- Enrolled 2 October 2020 to 12 May 2023
- 1 intervention participant excluded (prepregnancy diabetes); pregnancy data of 1 control participant excluded (twin pregnancy)
Primary result
2-h plasma glucose in OGTT
Mean difference
0.48 mmol/L
95% CI −0.05 to 1.01
P = 0.08
Interventionvs Control
mean difference 0.48 mmol/L (95% CI −0.05 to 1.01); P = 0.08
As reported in the abstract
Further findings
Adherence to prespecified criteria (intervention)
- Adhered in prepregnancy period
- 31/83 (37%)
- Fulfilled criteria among those who became pregnant
- 24/55 (44%)
Intervention components in prepregnancy period
- Average eating window, hours/day (SD 1.2)
- 9.9
- Average weekly PAI points (SD 54)
- 111
- Adherence to both components decreased during pregnancy
Original publication
Time restricted eating and exercise training before and during pregnancy for people with increased risk of gestational diabetes: single centre randomised controlled trial (BEFORE THE BEGINNING). BMJ. Published 9 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →