Gestational diabetes & diabetes in pregnancy

Gestational diabetes mellitus in women with polycystic ovary syndrome

Diabetes MetabPublished Observational cohort study

Authors' conclusion

The prevalence of GDM in women with PCOS is not similar between those treated for infertility using ART and those not treated. Other determinants of GDM within this population have been identified, which could potentially enable early detection of women at risk and the implementation of personalized care in a precision medicine approach.

Study context

Population
Pregnant women with polycystic ovary syndrome (PCOS) followed up 1997–2024 at the university hospital centre where PCOS was diagnosed
Participants
622 women
Exposure
Infertility-treated vs untreated women with PCOS
  • Treatedn = 301
  • Untreatedn = 321reference
Outcome
Prevalence of GDM
Methodological detailssingle-centre (university hospital centre)
  • Single-centre (university hospital centre)

Main finding

As reported in the abstract

GDM prevalence

P = 0.04

Gestational diabetes mellitus (GDM) prevalence in total population
32.5% (95% CI 28.8-36.3)

Observational data: associations, not effects.

Further findings

OutcomeP value
Time to initiation of insulin therapySimilarLog-rank test P = .83

Independent risk factors for GDM (logistic regression)

Age, BMI, blood pressure, TG, testosterone and LH were independent risk factors for GDM

Original publication

Gestational diabetes mellitus in women with polycystic ovary syndrome. Diabetes Metab. Published 19 March 2026. doi:10.1016/j.diabet.2026.101755

Composed by AI from the published abstract and checked against it. How Briefs are made →

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