Gestational diabetes & diabetes in pregnancy

Gestational diabetes mellitus in low- and middle-income countries: a systematic review and meta-analysis of associated factors

Diabetes Res Clin PractPublished Systematic review and meta-analysis of observational studies

Authors' conclusion

This study found that advanced maternal age, pre-pregnancy obesity, family history of diabetes, prior GDM, pre-hypertension, preeclampsia, and PCOS are key factors associated with GDM in LMICs.

Study context

Population
Observational studies published in Low- and Middle-Income Countries (LMICs) between 2015 and August 202547 studies
Outcome
Factors associated with GDM
Methodological detailsrandom-effects model, pre-registered protocol, Seven databases searched (PubMed, CINAHL, PsycINFO, Scopus, EMBASE, CABI, Google Scholar), Heterogeneity evaluated by I2; random-effects pooled estimates
  • Random-effects model
  • Pre-registered protocol
  • Seven databases searched (PubMed, CINAHL, PsycINFO, Scopus, EMBASE, CABI, Google Scholar)
  • Heterogeneity evaluated by I2; random-effects pooled estimates

Pooled result

As reported in the abstract

Factors associated with increased risk of GDM
  • Significantly associated with increased Gestational Diabetes Mellitus (GDM) risk: maternal age ≥ 30, multiparity, urban residence, pre-pregnancy obesity BMI ≥ 25 kg/m², family history of diabetes, history of GDM, pre-hypertension, preeclampsia, polycystic ovarian syndrome (PCOS) and physical inactivity
  • 116 factor-specific effect estimates

Original publication

Gestational diabetes mellitus in low- and middle-income countries: a systematic review and meta-analysis of associated factors. Diabetes Res Clin Pract. Published 18 March 2026. doi:10.1016/j.diabres.2026.113207

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