An Exploration of Mineral Density, Elemental and Chemical Composition of Primary Teeth in Relation to Cord-Blood Vitamin D, Using Laboratory Analysis Techniques
Authors' conclusion
Although subtle, the differences seen suggest further attention should be given to children with known milder levels of vitamin D deficiency in early life.
Study context
- Population
- Exfoliated primary incisors from participants with known 25-hydroxyvitamin D levels at birth
- Participants
- 63 exfoliated primary incisors
- Comparison
- Primary teeth by cord-blood 25-OHD status at birth
- Outcome
- Mineral density, total density and elemental composition of enamel and dentine
Methodological detailslaboratory analysis, μCT, EDX and Raman spectroscopy
- Laboratory analysis
- μCT, EDX and Raman spectroscopy
Main finding
As reported in the abstract
- No differences in mineralization and chemical composition by μCT and EDX, irrespective of 25-OHD status
- Subtle structural differences by Raman spectroscopy: more crystalline enamel with sufficient 25-OHD at birth
Original publication
An Exploration of Mineral Density, Elemental and Chemical Composition of Primary Teeth in Relation to Cord-Blood Vitamin D, Using Laboratory Analysis Techniques. J Bone Miner Res. Published 16 November 2023. doi:10.
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