Electrical stimulation paradigms on muscle quality and bone mineral density after spinal cord injury
Authors' conclusion
NMES-RT + FES enhanced muscle quality as measured by torque production and muscle CSA as result of increasing ankle weights. The addition of FES- lower extremity cycling to NMES-RT maintained but did not further augment muscle quality. Furthermore, NMES-RT + FES may help maintain BMD after SCI.
Study context
- Population
- Persons with spinal cord injury (SCI)
- Participants
- 32 persons
- Comparison
- Neuromuscular electrical stimulation-resistance training (NMES-RT) followed by functional electrical stimulation (FES)-lower extremity cycling vs passive movement training (PMT) followed by FES-lower extremity cycling
- NMES-RT + FESn = 16
- PMT + FESn = 16reference
- Primary endpoint
- Muscle quality (peak torque and muscle CSA) and BMD
Primary result
As reported in the abstract
Muscle quality (torque and muscle CSA) · P1 (12 weeks)
Difference
11.0 cm²
P = 0.007
left whole thigh muscle CSA; greater with NMES-RT + FES
Difference
8.0 cm²
P = 0.001
Knee extensor (KE) muscle CSA; greater with NMES-RT + FES
Further findings
Ankle weights and muscle measures in NMES-RT + FES · following P1
- Ankle weights positively associated with muscle CSA, isometric and isokinetic torques and muscle quality
Original publication
Electrical stimulation paradigms on muscle quality and bone mineral density after spinal cord injury. Osteoporos Int. Published 22 April 2025. doi:10.
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