Osteoporosis, bone & mineral

Opportunistic assessment of osteoporosis using hip and pelvic X-rays with OsteoSight™: validation of an AI-based tool in a US population

Osteoporos IntPublished Diagnostic accuracy study

Authors' conclusion

The results demonstrate that OsteoSight is accurate in identifying patients with low BMD.

Study context

Population
US population with routine hip and pelvic X-rays
Comparison
OsteoSight™ AI analysis of hip and pelvic X-rays vs DXA
Outcome
Diagnostic accuracy in identifying low BMD vs DXA
Methodological detailsvalidation study, pre-specified acceptance criteria
  • Validation study
  • Pre-specified acceptance criteria

Performance

As reported in the abstract

Identification of patients at risk of low BMD
Test or modelAUCSpecificitySensitivity
OsteoSight0.834 [0.789-0.880]0.852 [0.783-0.930]0.628 [0.538-0.743]

OsteoSight

AUC0.834 [0.789-0.880]
Specificity0.852 [0.783-0.930]
Sensitivity0.628 [0.538-0.743]

Further findings

Pre-processing pipeline

Successfully excluded unsuitable cases including incorrect body parts, metalwork, and unacceptable femur positioning

Original publication

Opportunistic assessment of osteoporosis using hip and pelvic X-rays with OsteoSight™: validation of an AI-based tool in a US population. Osteoporos Int. Published 22 April 2025. doi:10.1007/s00198-025-07487-0

Composed by AI from the published abstract and checked against it. How Briefs are made →

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