Effects of non‐nutritive sweetened beverages versus water after a 12‐week weight‐loss program: A randomized controlled trial
Primary result · Weight changeResult — go to the resultDifference −0.2 kg 90% CI −0.7 to 0.4Authors' conclusion
Weight loss was equivalent with NNS beverages and water following a 12-week behavioral weight-management program.
Study context
- Population
- Adults with BMI 27 to 35 kg/m² who regularly drank cold beverages, undergoing a weekly 12-week group behavioral weight-management program; 24.1% non-nutritive sweetened (NNS) beverage naïverandomized 1:1
- Participants
- 493 adults
- Comparison
- NNS beverages vs water during a 12-week behavioral weight-management program
- NNS beveragesn = 247
- Watern = 246reference
- Primary endpoint
- Weight change (equivalence: two-sided p > 0.05)
- Follow-up
- Week 12
Methodological detailsongoing 2-year, parallel-group, open-label, controlled equivalence trial, week-12 data reported
- Ongoing 2-year
- Parallel-group
- Open-label
- Controlled equivalence trial
- week-12 data reported
Primary result
Weight change
Difference
−0.2 kg
90% CI −0.7 to 0.4
Change by group
NNS beverages
−5.8
kg
Water
−5.6
kg
NNS beveragesvs Water
difference −0.2 kg (90% CI −0.7 to 0.4)
As reported in the abstract
Secondary outcomes
Waist circumference reduction · week 12
- Reduction in waist circumference greater with NNS beverages vs water
HbA1c and sweetener consumption reduction · week 12
- Reductions in HbA1c and consumption of any type of sweetener greater with water vs NNS beverages
Other secondary end points · week 12
- No significant differences between groups for other secondary end points (hip circumference, blood pressure, lipids, liver function, hunger, activity)
Original publication
Effects of non‐nutritive sweetened beverages versus water after a 12‐week weight‐loss program: A randomized controlled trial. Obesity (Silver Spring). Published 21 July 2023. doi:10. 1002/ oby. 23796
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