Obesity

Body composition and risk factors for cardiovascular disease in global multi-ethnic populations

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

There were distinct patterns of adiposity and body composition and cardiovascular risk factors across ethnic groups. We need to better understand the mechanisms relating body composition with cardiovascular risk to attenuate the increasing global burden of obesity-related disease.

Study context

Population
Adults from The Malaysian Cohort (Malay, Indian, Chinese) and UK Biobank (White)
Participants
30,721 / 10,865 / 25,296 / 413,737
Exposure
Associations of body composition with CVD risk factors across ethnic groups
  • Malayn = 30,721
  • Indiann = 10,865
  • Chinesen = 25,296
  • Whiten = 413,737
Outcome
Associations of BMI, WC, fat mass and appendicular lean mass with SBP, LDL-C, TG and HbA1c
Methodological detailspopulation-based surveys, multi-ethnic, sex-specific linear regression
  • Population-based surveys
  • Multi-ethnic
  • Sex-specific linear regression

Main finding

As reported in the abstract

Associations of body composition with CVD risk factors

Association of BMI with TG in men, Indian (per 5 kg/m² BMI)

0.09 [0.02] mmol/L

Association of BMI with TG in men, Chinese (per 5 kg/m² BMI)

0.38

0.02

Observational data: associations, not effects.

Original publication

Body composition and risk factors for cardiovascular disease in global multi-ethnic populations. Int J Obes (Lond). Published 17 July 2023. doi:10.1038/s41366-023-01339-9

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