Obesity

A Cardiovascular Disease (CVD) Classification Model for Individuals With Obesity: Multi‐Ethnic Validation Based on Multiple Metabolic Indicators

Obesity (Silver Spring)Published Prediction model development and validation study

Authors' conclusion

This study developed and validated a nomogram for the classification of prevalent CVD in individuals with obesity, providing a validated model optimized for the population with obesity.

Study context

Population
Individuals with obesity; sensitivity analysis with a unified BMI standard in the Korea cohort
Comparison
Internal validation vs External validation
Outcome
Classification of prevalent CVD (model performance: AUC, calibration, decision curve analysis (DCA))
Methodological detailsinternal and external validation, LASSO regression, multivariate logistic model, nomogram, Web-based dynamic nomogram implemented
  • Internal and external validation
  • LASSO regression
  • Multivariate logistic model
  • Nomogram
  • Web-based dynamic nomogram implemented

Performance

As reported in the abstract

Model discrimination and calibration
Test or modelAUCHosmer-Lemeshow p value
Internal validation0.7990.823
External validation0.8210.083

AUC

Internal validation0.799
External validation0.821

Hosmer-Lemeshow p value

Internal validation0.823
External validation0.083

Original publication

A CVD Classification Model for Individuals With Obesity: Multi‐Ethnic Validation Based on Multiple Metabolic Indicators. Obesity (Silver Spring). Published 21 July 2026. doi:10.1002/oby.70265

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