Electronic phenotypes to distinguish clinician attention to high body mass index, hypertension, lipid disorders, fatty liver and diabetes in pediatric primary care: Diagnostic accuracy of electronic phenotypes compared to masked comprehensive chart review
Authors' conclusion
Electronic phenotypes for clinician attention to overweight/obesity and distinct comorbidities are highly specific, with moderate (BMI) to modest (each comorbidity) sensitivity. The high specificity supports using phenotypes to identify children with prior high-BMI/comorbidity attention.
Study context
- Population
- Children aged 2–18 years with overweight/obesity in pediatric primary care817 visit-records reviewed
- Participants
- 17,397 children
- Comparison
- Electronic phenotypes of clinician attention vs masked comprehensive chart review
- Outcome
- Operating characteristics of each clinician-attention phenotype vs masked chart review
Methodological detailsmasked comprehensive chart review as reference
- Masked comprehensive chart review as reference
Performance
As reported in the abstract
Diagnostic accuracy of electronic phenotypes
| Test or model | Sensitivity | PPV | NPV |
|---|---|---|---|
| Hypertension | 69% | 100% | 98.9% |
| High body mass index (BMI) | 84.7% | — not stated in the abstract | 92.3% |
| Lipid disorders | — not stated in the abstract | 100% | — not stated in the abstract |
| Prediabetes/diabetes | — not stated in the abstract | 96.8% | — not stated in the abstract |
Sensitivity
Hypertension69%
High body mass index (BMI)84.7%
Lipid disorders— not stated in the abstract
Prediabetes/diabetes— not stated in the abstract
PPV
Hypertension100%
High body mass index (BMI)— not stated in the abstract
Lipid disorders100%
Prediabetes/diabetes96.8%
NPV
Hypertension98.9%
High body mass index (BMI)92.3%
Lipid disorders— not stated in the abstract
Prediabetes/diabetes— not stated in the abstract
— not stated in the abstract
- Specificity of each electronic phenotype
- 99%-100%
- Sensitivity range across attention classifications
- 69% to 84.7%
Original publication
Electronic phenotypes to distinguish clinician attention to high body mass index, hypertension, lipid disorders, fatty liver and diabetes in pediatric primary care: Diagnostic accuracy of electronic phenotypes compared to masked comprehensive chart review. Pediatr Obes. Published 17 July 2023. doi:10.
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