Obesity

Non-nutritive sweetened beverages versus water after a 52-week weight management programme: a randomised controlled trial

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

During a 52-week behavioural weight management programme, water and NNS beverages were non-equivalent, with weight loss maintained to a statistically greater extent with NNS beverages compared with water. However, this difference was not clinically significant.

Study context

Population
Adults with BMI 27–35 kg/m² who regularly consumed cold beverages, in a group behavioural weight management programme (12-week weight-loss phase, 40-week maintenance phase); 24.1% non-nutritive sweetened (NNS)-naïverandomised 1:1
Participants
493 adults
Comparison
NNS beverages vs water
  • NNS beveragesn = 247
  • Watern = 246reference
Primary endpoint
Weight change (equivalence: two-sided P > 0.05)
Follow-up
Week 52
Methodological detailsparallel-group, open-label, controlled equivalence trial
  • Parallel-group
  • Open-label
  • Controlled equivalence trial

Primary result

Weight loss maintained · 52 weeks

Difference

1.4 kg

90% CI −2.6 to −0.2

P < 0.05

By group

As reported in the abstract

Original publication

Non-nutritive sweetened beverages versus water after a 52-week weight management programme: a randomised controlled trial. Int J Obes (Lond). Published 5 October 2023. doi:10.1038/s41366-023-01393-3

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