Assessing the value for money, from a policy maker perspective, of 24 randomised controlled trial designs for an online weight maintenance guided self-help intervention: an expected value of sample information analysis
Authors' conclusion
Investment in a large RCT to evaluate the SWiM intervention for patients completing a range of weight loss interventions offers the greatest value to the NHS.
Study context
- Population
- Simulated randomised controlled trial (RCT) populations of participants completing weight management programmes (behavioural, specialist-led, diabetes prevention programme, T2D remission, digital, all weight management services), UK National Health Service (NHS)24 RCT designs
- Comparison
- Online weight maintenance guided self-help (Supporting Weight Management (SWiM)) vs usual care; 24 RCT designs varying inclusion criteria, trial duration (1-2 years) and sample size (n = 500 or 2000)
- Outcome
- Trial benefits (reduction in the costs of an inefficient decision for future populations) vs trial costs; value for money if benefits exceed costs
- Follow-up
- 10 years
Methodological detailshealth economic model, structured expert elicitation (4 experts), 24 simulated RCT designs, policy maker perspective
- Health economic model
- Structured expert elicitation (4 experts)
- 24 simulated RCT designs
- Policy maker perspective
Main finding
As reported in the abstract
Trial benefits vs trial costs
- Behavioural weight management, diabetes prevention programme or all weight loss programmes inclusion criteria: trial designs with greater benefits than costs
- 12
Original publication
Assessing the value for money, from a policy maker perspective, of 24 randomised controlled trial designs for an online weight maintenance guided self-help intervention: an expected value of sample information analysis. Int J Obes (Lond). Published 22 May 2025. doi:10. 1038/ s41366-025-01804-7
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