Obesity

Assessing the value for money, from a policy maker perspective, of 24 randomised controlled trial designs for an online weight maintenance guided self-help intervention: an expected value of sample information analysis

Int J Obes (Lond)Published Expected value of sample information analysis

Authors' conclusion

Investment in a large RCT to evaluate the SWiM intervention for patients completing a range of weight loss interventions offers the greatest value to the NHS.

Study context

Population
Simulated randomised controlled trial (RCT) populations of participants completing weight management programmes (behavioural, specialist-led, diabetes prevention programme, T2D remission, digital, all weight management services), UK National Health Service (NHS)24 RCT designs
Comparison
Online weight maintenance guided self-help (Supporting Weight Management (SWiM)) vs usual care; 24 RCT designs varying inclusion criteria, trial duration (1-2 years) and sample size (n = 500 or 2000)
Outcome
Trial benefits (reduction in the costs of an inefficient decision for future populations) vs trial costs; value for money if benefits exceed costs
Follow-up
10 years
Methodological detailshealth economic model, structured expert elicitation (4 experts), 24 simulated RCT designs, policy maker perspective
  • Health economic model
  • Structured expert elicitation (4 experts)
  • 24 simulated RCT designs
  • Policy maker perspective

Main finding

As reported in the abstract

Trial benefits vs trial costs
Behavioural weight management, diabetes prevention programme or all weight loss programmes inclusion criteria: trial designs with greater benefits than costs
12

Original publication

Assessing the value for money, from a policy maker perspective, of 24 randomised controlled trial designs for an online weight maintenance guided self-help intervention: an expected value of sample information analysis. Int J Obes (Lond). Published 22 May 2025. doi:10.1038/s41366-025-01804-7

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