Gestational diabetes & diabetes in pregnancy
Earlier detection of gestational diabetes impacts on medication requirements, neonatal and maternal outcomes
Authors' conclusion
Timely diagnosis and personalized treatment of GD are desirable because an earlier presentation is related to a higher risk of adverse neonatal and maternal outcomes.
Study context
- Population
- Pregnant women with gestational diabetes (GD) who underwent a 75-g OGTT
- Participants
- 369 women
- Exposure
- Early GD diagnosis vs diagnosis after 24 weeks
- Outcome
- Neonatal hypoglycaemia and respiratory distress syndrome
Methodological detailst-tests, χ2 tests and logistic regression; p < .05 significant
- T-tests, χ2 tests and logistic regression; p < .05 significant
Main finding
As reported in the abstract
Odds ratio
18.57
P = 0.013
neonatal hypoglycaemia
Odds ratio
4.75
P = 0.034
respiratory distress syndrome
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Pharmacotherapy requirementeGDvs GD after 24 weeksNutritional therapy prescription + metformin | 2.26 (1.25–4.09) | P = 0.007 | |
| Maternal post-partum hyperglycaemia at 2 h of OGTT | 1.03 (1.02–1.13) | P = 0.024 | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | P value |
|---|---|
| Pharmacotherapy requirementeGD vs GD after 24 weeks | P = 0.027 |
- Pharmacotherapy requirement: more frequent specialized nutritional consulting + metformin with early GD (eGD)
Pharmacotherapy requirement
- Nutritional therapy by an accredited nutritionist was the most common treatment in women diagnosed after 24 weeks
Original publication
Earlier detection of gestational diabetes impacts on medication requirements, neonatal and maternal outcomes. Diabetes Obes Metab. Published 3 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →