Association of time in tight range and 1,5‐anhydroglucitol in type 2 diabetes
Study context
- Population
- Moderately controlled patients with T2D on a stable treatment regimen; Time in tight range (TITR) and TIR measured with continuous glucose monitoring (CGM)
- Participants
- 1,531 participants
- Outcome
- Relationship between serum anhydroglucitol and TITR (Spearman correlation); predictive efficacy of serum anhydroglucitol for identifying TITR > 50% (ROC curves)
Main finding
As reported in the abstract
- Serum anhydroglucitol positively correlated with TITR (Spearman)
- p < 0.001
- Optimal serum anhydroglucitol cut-off for TITR >50%
- 8.0 μg/mL
- AUC for identifying TITR >50%
- 0.693 (0.667, 0.719)
Observational data: associations, not effects.
Further findings
Serum anhydroglucitol combined with fasting glucose or 2-hour postprandial glucose for identifying TITR > 50%
- Combination further improved predictive power (both)
- P < 0.001
Subgroups: serum anhydroglucitol for TITR > 50%
- Acceptable predictive accuracy across all subgroups (AUCs around 0.700)
Median levels in total population
- Median serum anhydroglucitol
- 7.4 (4.4, 12.1) μg/mL
- Median haemoglobin A1c (HbA1c)
- 7.0% (6.4%, 7.5%)
- Median TITR
- 52.0% (32.0%, 69.0%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association of time in tight range and 1,5‐anhydroglucitol in type 2 diabetes. Diabetes Obes Metab. Published 9 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →