Association between weight changes and infective endocarditis in patients with diabetes: A nationwide population-based cohort study
Authors' conclusion
Both weight gain and weight loss are associated with an increased incidence of IE, and the greater the degree of weight change, the greater the risk.
Study context
- Population
- Korean patients with DM aged ≥20 years who underwent health screenings twice in a 2-year interval between 2009 and 2012; followed up until December 2018
- Participants
- 1,762,108 patients
- Exposure
- Weight change categories vs stable weight
- Severe weight lossn = 67,580
- Moderate weight lossn = 247,969
- Stable weightn = 1,267,849reference
- Moderate weight gainn = 135,774
- Severe weight gainn = 42,936
- Outcome
- Incidence of infective endocarditis (IE)
- Follow-up
- Median 5.21 years
Methodological detailsnationwide, Korean
- Nationwide
- Korean
Main finding
As reported in the abstract
Infective endocarditis (adjusted) · median 5.21 years
Each group vs stable weightHazard ratio (95% CI)
Severe weight loss
2.41(1.87–3.12)
Moderate weight loss
1.28(1.05–1.55)
Moderate weight gain
1.17(0.91–1.50)
Severe weight gain
1.59(1.11–2.28)
- Cases of infective endocarditis (IE) during follow-up (all groups)
- 828
Observational data: associations, not effects.
Original publication
Association between weight changes and infective endocarditis in patients with diabetes: A nationwide population-based cohort study. Int J Obes (Lond). Published 21 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →