Lipids & metabolic liver disease
Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study
Authors' conclusion
Elevated levels of the TyG index were positive associated with prevalence of uncontrolled hypertension and arterial stiffness among US adults with hypertension.
Study context
- Population
- US adults with hypertension, NHANES 1999–2018
- Participants
- 8,513 adults
- Exposure
- Triglyceride-glucose (TyG) index quartiles
- Outcome
- Arterial stiffness (estimated pulse wave velocity, ePWV) and uncontrolled hypertension
Methodological detailspopulation-based, NHANES 1999-2018
- Population-based
- NHANES 1999-2018
Main finding
As reported in the abstract
Uncontrolled hypertension
Odds ratio (95% CI)
Q3vs Q1
1.28(1.06–1.52)
Q4vs Q1
1.49(1.21–1.89)
- Overall prevalence of uncontrolled hypertension
- 54.3%
- Arterial stiffness: β for ePWV per TyG index, 95% CI 0.00-0.08, P = 0.039
- 0.04
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Uncontrolled hypertension, subgroup taking antihypertensive medicationQ4vs Q1 | 2.03 (1.37–3.11) | |
| 0.20.5125Odds ratio (log scale) |
HOMA-IR and uncontrolled hypertension / arterial stiffness
- HOMA-IR showed no significant positive correlation to uncontrolled hypertension or arterial stiffness
Original publication
Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study. Cardiovasc Diabetol. Published 9 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →