Diabetes technology

Accuracy of Glucose Trends by Subcutaneous Continuous Monitoring vs Intermittent Arterial Measurements in Critically Ill Patients

J Diabetes Sci TechnolPublished Accuracy study

Authors' conclusion

In critically ill patients receiving insulin, CGM demonstrated high overall trend accuracy relative to ABG. Trend accuracy was reduced at lower glucose ranges and during the initial 24 hours of CGM use.

Study context

Population
Adult intensive care unit (ICU) patients receiving insulin and organ-supportive therapies2,701 paired trends
Participants
40 patients
Comparison
Subcutaneous continuous glucose monitoring (CGM) vs intermittent arterial blood gas measurements
Outcome
Trend accuracy by Rate Error Grid Analysis (R-EGA) and DTS Trend Accuracy Matrix (DTS-TAM)

Performance

As reported in the abstract

Trend accuracy of CGM vs ABG

Trends in Rate Error Grid Analysis (R-EGA) Zone A

99.7%

Trends in R-EGA Zone B

0.3%

Trends in Diabetes Technology Society Trend Accuracy Matrix (DTS-TAM) No Risk category

98.6%

Trends in adjacent Mild-to-Moderate Risk categories

1.7%

Further findings

Mild-to-Moderate Risk trends by arterial blood gas (ABG) level

ABG <100 mg/dL (5.56 mmol/L)
3.6%
ABG 100 to 180 mg/dL (5.56 to 10 mmol/L)
1.3%
ABG >180 mg/dL (10 mmol/L)
1.6%

Mild-to-Moderate Risk trends over time from CGM initiation

First 24 hours of CGM use
2.9%
Beyond 24 hours
0.9%

Original publication

Accuracy of Glucose Trends by Subcutaneous Continuous Monitoring vs Intermittent Arterial Measurements in Critically Ill Patients. J Diabetes Sci Technol. Published 24 July 2025. doi:10.1177/19322968251358830

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