Accuracy of an Interstitial Continuous Glucose Management System in Critically Ill Patients: A Prospective Observational Study
Authors' conclusion
Dexcom G7 showed acceptable accuracy during stable ICU conditions, but performance deteriorated during rapid glucose excursions.
Study context
- Population
- Critically ill adults with stress hyperglycemia, no prior diabetes, expected intensive care unit (ICU) stay ≥5 days
- Participants
- 20 adults
- Exposure
- Dexcom G7 continuous glucose monitoring (CGM) vs arterial blood glucose
- Outcome
- CGM accuracy vs arterial reference glucose, outside IVGTT
- Follow-up
- First 10 ICU days
Methodological detailsancillary study of the Determination of Insulin Resistance in ICU (DIRICU) study, post hoc 20-minute temporal shift analysis
- Ancillary study of the DIRICU study
- Post hoc 20-minute temporal shift analysis
Main finding
As reported in the abstract
- Paired values
- 716
- R2
- .58
- Mean bias
- +11 mg/dL
- Mean absolute relative difference (MARD)
- 17%
- Values in Clarke zones A/B
- 98.9%
Observational data: associations, not effects.
Further findings
CGM accuracy vs arterial reference glucose, during intravenous glucose tolerance tests (IVGTT)
- Paired values
- 1018
- R2
- .028
- Mean bias
- −34 mg/dL
- MARD
- 24%
- Values in zones A/B
- 80.3%
- Values in zone D
- 18.6%
- Accuracy deteriorated markedly
CGM accuracy during IVGTT after 20-minute temporal shift
- R2
- .34
- MARD
- 19%
- Values in zones A/B
- 94.7%
- Post hoc analysis
Safety
- Sensor-related adverse events
- 0
Original publication
Accuracy of an Interstitial Continuous Glucose Management System in Critically Ill Patients: A Prospective Observational Study. J Diabetes Sci Technol. Published 21 September 2026. doi:10.
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