Diabetes technology

Agreement of Over-the-Counter Continuous Glucose Monitors With Capillary-Meter Glucose in Young Adults Without Diabetes

J Diabetes Sci TechnolPublished Agreement study

Authors' conclusion

Over-the-counter continuous glucose monitors seemingly agreed with overall capillary glucose trends but were less reliable for exact-value agreement.

Study context

Population
Participants without diabetes (young adults)
Participants
39 participants
Comparison
OTC CGM vs capillary-meter glucose
Outcome
Agreement of OTC CGM with capillary-meter glucose
Methodological detailssessions combining rest or exercise with placebo or sugar-sweetened drink consumption
  • Sessions combining rest or exercise with placebo or sugar-sweetened drink consumption

Main finding

As reported in the abstract

Agreement of OTC CGM with capillary-meter glucose (overall)

Overall mean absolute relative difference (MARD)

12.9%

Mean bias

−4.8 mg/dL

Within-15%/15-mg/dL agreement

66.5%

Further findings

MARD by drink: sugar vs placebo

P < 0.01

Exercise and glucose dynamics

Exercise had no consistent effect
Disagreement increased with faster rates of change and, less consistently, higher glucose

CGM delay

MARD with uniform 5-minute delay
11.2% (P < .001)
Population lag by cross-correlation
6.2-minute

Interparticipant differences

Interparticipant agreement differed significantly, unattributable to measured biological variables
Participant/device identity explained direction of error more than magnitude
High-MARD participants did not have consistent high MARD across conditions

Safety

CGM change-indicator directional arrows classified as moderate to extreme risk

Arrows classified as moderate to extreme risk
13.8%

Original publication

Agreement of Over-the-Counter Continuous Glucose Monitors With Capillary-Meter Glucose in Young Adults Without Diabetes. J Diabetes Sci Technol. Published 20 September 2026. doi:10.1177/19322968261482150

Composed by AI from the published abstract and checked against it. How Briefs are made →

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