Beyond glycemic metrics: Real-world benefits of connected insulin pens in type 1 diabetes
Authors' conclusion
Connected insulin pens enhanced glycemic control, mitigated glucose variability and improve patient-reported outcomes.
Study context
- Population
- People with T1D treated with MDI and CGM; no change in treatment regimen or insulin type
- Participants
- 220 people
- Exposure
- After vs before 12 weeks of connected insulin pens
- Outcome
- Glucose control and patient-reported outcomes
- Follow-up
- 12 weeks
Methodological detailsmulticentre, real-life clinical practice, before-after (baseline vs 12 weeks)
- Multicentre
- Real-life clinical practice
- Before-after (baseline vs 12 weeks)
Main finding
As reported in the abstract
12 weeks
- Time in range (TIR), hypoglycaemia awareness and patient-reported outcomes improved and HbA1c decreased
- Time with glucose 120-140 mg/dl increased; time 240-300 mg/dl decreased
Observational data: associations, not effects.
Further findings
Omitted and delayed insulin doses
%
- Omission of basal insulin doses
- 33.8
- Omission of prandial insulin doses
- 65.7
- Delayed injections
- 90.5
Impact of omitted and delayed doses on glycaemic control
- Basal omission had greater impact than prandial omissions: increase in variability indexes and time above range, decrease in TIR and TTIR
- 10/16 variability indexes
- Delayed prandial doses increased variability parameters
- 7/16
Original publication
Beyond glycemic metrics: Real-world benefits of connected insulin pens in type 1 diabetes. Diabetes Res Clin Pract. Published 20 July 2025. doi:10. 1016/ j. diabres. 2025. 112377
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