Accelerometer-measured “weekend warrior” physical activity and incident cardiovascular disease in adults with type 2 diabetes mellitus or prediabetes: A prospective cohort study
Authors' conclusion
The active WW pattern, concentrating guideline-recommended MVPA into 1-2 days, was similar to the active regular pattern in reducing the risk of CVD in adults with T2DM or prediabetes.
Study context
- Population
- Adults with T2D or prediabetes aged 43–78 years with accelerometer data, UK Biobank1,128 cardiovascular disease (CVD) cases
- Participants
- 10,989 adults
- Exposure
- Active weekend warrior (WW) and active regular PA patterns vs inactive pattern
- Outcome
- Incident overall CVD, myocardial infarction (MI), atrial fibrillation (AF), heart failure (HF) and stroke from hospital and death records
- Follow-up
- Median 7.86 years
Methodological detailsaccelerometer-measured physical activity, UK Biobank
- Accelerometer-measured physical activity
- UK Biobank
Main finding
As reported in the abstract
Overall CVD, MI, AF, HF
Each group vs inactiveHazard ratio (95 % CI)
Active WWoverall CVD
0.72(0.63–0.83)
Active WWMI
0.66(0.51–0.85)
Active WWAF
0.70(0.58–0.85)
Active WWHF
0.66(0.51–0.86)
Active regularoverall CVD
0.75(0.64–0.89)
Active regularMI
0.58(0.42–0.80)
Active regularAF
0.85(0.68–1.05)
Active regularHF
0.51(0.36–0.72)
Observational data: associations, not effects.
Original publication
Accelerometer-measured “weekend warrior” physical activity and incident cardiovascular disease in adults with type 2 diabetes mellitus or prediabetes: A prospective cohort study. Diabetes Res Clin Pract. Published 15 October 2025. doi:10.
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