Accelerometer-derived “weekend warrior” physical activity pattern and incident type 2 diabetes
Authors' conclusion
Engaging in the weekend warrior pattern is associated with a similarly lower risk of T2D to the regularly active pattern, even among individuals with high genetic risk. These findings highlight the weekend warrior pattern as a significant and flexible alternative in preventive intervention strategies for T2D, particularly for those unable to maintain daily activity routines.
Study context
- Population
- UK Biobank general participants with validated accelerometry data (wrist triaxial accelerometer worn one week), free of T2D2,464 T2D cases
- Participants
- 84,656 participants
- Exposure
- Weekend warrior and regularly active physical activity (PA) patterns vs inactive
- Outcome
- Incident T2D
- Follow-up
- Median 8.4 years
Methodological detailsUK Biobank, accelerometer-derived physical activity, multivariable-adjusted
- UK Biobank
- Accelerometer-derived physical activity
- Multivariable-adjusted
Main finding
As reported in the abstract
Each group vs inactiveHazard ratio (95% CI)
Weekend warrior
0.75(0.67–0.84)
Regularly active
0.80(0.69–0.94)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Incident T2D by T2D genetic risk score (PRS): weekend warrior vs inactiveWeekend warriorvs InactiveHigher PRS | 0.78 (0.67–0.91) | |
| Incident T2D by T2D genetic risk score (PRS): weekend warrior vs inactiveWeekend warriorvs InactiveIntermediate PRS | 0.78 (0.62–0.97) | |
| Incident T2D by T2D genetic risk score (PRS): weekend warrior vs inactiveWeekend warriorvs InactiveLowest PRS | 0.59 (0.43–0.80) | |
| 0.512Hazard ratio (log scale) |
Original publication
Accelerometer-derived “weekend warrior” physical activity pattern and incident type 2 diabetes. Cardiovasc Diabetol. Published 21 March 2025. doi:10. 1186/ s12933-025-02676-x
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