Accelerometer‐Derived ‘Weekend Warrior’ Physical Activity Pattern and Microvascular Risk in Individuals With Type 2 Diabetes and Prediabetes
Authors' conclusion
Concentrating recommended weekly MVPA within 1-2 days offers similar microvascular protection as regularly distributed activity among individuals with T2D and prediabetes
Study context
- Population
- Adults with T2D and prediabetes with accelerometer-measured data, UK Biobank
- Participants
- 12,923 adults
- Exposure
- Active weekend warrior and active regular MVPA patterns vs inactive
- Outcome
- Incident microvascular complications
- Follow-up
- Median 7.88 years
Methodological detailsUK Biobank, accelerometer-measured physical activity, Cox proportional hazards models
- UK Biobank
- Accelerometer-measured physical activity
- Cox proportional hazards models
Main finding
As reported in the abstract
Each group vs inactiveHazard ratio (95% CI)
Active WW
0.71(0.61–0.82)
Active regular
0.63(0.52–0.77)
- Incident microvascular complications documented
- 1235
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| DKD, DN and DRActive WW vs Active regular | all p > 0.05 |
DKD, DN and DR
- Protective associations extended consistently to DKD, DN and DR, with no statistically significant differences between weekend warrior (WW) and regularly active
Alternative MVPA thresholds, subgroup and sensitivity analyses
- Findings robust across alternative MVPA thresholds, subgroup analyses and sensitivity analyses
Original publication
Accelerometer‐Derived ‘Weekend Warrior’ Physical Activity Pattern and Microvascular Risk in Individuals With Type 2 Diabetes and Prediabetes. Diabetes Obes Metab. Published 27 April 2026. doi:10. 1111/ dom. 70828
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