Diabetes complications

Wound healing and healing process in patients with diabetic foot ulcers: A survival analysis study

Diabetes Res Clin PractPublished Prospective cohort study

Authors' conclusion

This is the first study showing that beliefs about DFU are significant predictors of DFU healing, and that health literacy is a significant predictor of a favorable healing process. Brief, comprehensive interventions should be implemented, at the treatment initial stage, in order to change misperceptions and to promote DFU literacy and better health outcomes.

Study context

Population
Patients with a chronic DFU, evaluated on health literacy, perceived stress, anxiety, depression and illness perceptions71 at 6 months
Participants
153 patients
Outcome
DFU healing and favorable healing process (wound area reduction), incl. time to achieve them
Methodological detailssurvival analysis, Cox proportional hazard models, Evaluated at baseline (n = 153), 2 months (n = 108) and 6 months (n = 71)
  • Survival analysis
  • Cox proportional hazard models
  • Evaluated at baseline (n = 153), 2 months (n = 108) and 6 months (n = 71)

Main finding

As reported in the abstract

DFU healed

56.1%

Favorable healing process

83.6%

Median time to healing

112 days

Median time to favorable process

30 days

Observational data: associations, not effects.

Original publication

Wound healing and healing process in patients with diabetic foot ulcers: A survival analysis study. Diabetes Res Clin Pract. Published 11 March 2023. doi:10.1016/j.diabres.2023.110623

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