Prevalence of painful diabetic peripheral neuropathy in type 2 diabetes mellitus and diabetic peripheral neuropathy: A nationwide cross-sectional study in mainland China
Authors' conclusion
In mainland China, more than half of the patients with DPN have neuropathic pain. Patients with older age, lower education level, longer duration of diabetes, lower LDL, increased UA, decreased eGFR, and comorbidities had an increased risk of PDPN.
Study context
- Population
- Patients with T2D and diabetic peripheral neuropathy (DPN), 25 provinces in mainland China, July–December 2017; median age 63 years
- Participants
- 25,710 patients
- Outcome
- Prevalence of painful diabetic peripheral neuropathy (PDPN)
Methodological detailsnationwide, 25 provinces
- Nationwide
- 25 provinces
Main finding
As reported in the abstract
Prevalence of PDPN
Painful diabetic peripheral neuropathy (PDPN)
14,699
57.2%
Observational data: associations, not effects.
Further findings
Risk factors independently associated with PDPN
- Age >40 years, education level, hypertension, MI, diabetes duration >5 years, DR, nephropathy, moderate total cholesterol, moderate and higher low-density lipoprotein (LDL), increased uric acid and decreased estimated glomerular filtration rate (eGFR) independently associated with PDPN
- all P < 0.05
- C-peptide vs low levels: moderate levels associated with higher risk, high levels with lower risk of PDPN
- all P < 0.001
Original publication
Prevalence of painful diabetic peripheral neuropathy in type 2 diabetes mellitus and diabetic peripheral neuropathy: A nationwide cross-sectional study in mainland China. Diabetes Res Clin Pract. Published 4 March 2023. doi:10.
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