Prevalence and risk factors of painful diabetic neuropathy: A systematic review and meta-analysis
Study context
- Population
- Individuals with diabetic peripheral neuropathy (DPN); observational studies on PDPN prevalence, 4 English and 3 Chinese databases, up to June 22, 202441 studies
- Outcome
- Global prevalence of PDPN among individuals with DPN
Pooled result
As reported in the abstract
Pooled global prevalence of PDPN
Pooled global prevalence of PDPN
46.7 %
95% CI 41.8–51.7
Further pooled results
Prevalence by diagnostic method for neuropathic pain (subgroup analysis)
- Significant differences between diagnostic methods; higher rates with neuropathic-specific pain scales
- P = 0.03
Prevalence by mean diabetes duration (subgroup analysis)
- Higher prevalence in studies with mean diabetes duration <10 years or >15 years
- P < 0.01
Risk factors for PDPN
- Older age, OR
- 1.02 (95% CI 1.01-1.04)
- Female gender, OR
- 1.58 (95% CI 1.19-2.11)
- BMI ≥ 30 kg/m², OR
- 1.62 (95% CI 1.43-1.83)
- Longer diabetes duration, OR
- 1.05 (95% CI 1.01-1.08)
- Nephropathy, OR
- 1.32 (95% CI 1.24-1.40)
Original publication
Prevalence and risk factors of painful diabetic neuropathy: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 17 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →