The impact of depression on healing outcomes in people with diabetes-related foot ulcers: A systematic review
Authors' conclusion
Depression may have a significant negative impact on healing outcomes in people with DFUs.
Study context
- Population
- People with diabetes-related foot ulcers (DFUs); MEDLINE, APA PsycINFO, CINAHL, Embase and Cochrane Library searched from inception (1976) to 11 March 2024
- Participants
- 1,392 people11 studies
- Comparison
- Depression vs no depression
- Outcome
- Healing outcomes: healed ulcer, change in ulcer size and/or changes in ulcer severity classification tool scores
Methodological detailsnarrative synthesis, Mixed Methods Appraisal Tool (MMAT) quality appraisal
- Narrative synthesis
- MMAT quality appraisal
Pooled result
As reported in the abstract
Impact of depression on DFU healing outcomes
Studies finding a significant negative impact (or association) of depression on healing outcomes
5
45.5 %
Studies finding no significant impact or association
6
54.5 %
Further pooled results
Study quality (MMAT)
- High quality
- 3 studies
- Medium quality
- 4 studies
- Low quality
- 4 studies
Original publication
The impact of depression on healing outcomes in people with diabetes-related foot ulcers: A systematic review. Diabetes Res Clin Pract. Published 22 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →