Vitamin D Insufficiency and Epistemic Humility: An Endocrine Society Guideline Communication
Recommendations
As issued by the authors
Available clinical trial evidence does not permit establishment of 25(OH)D thresholds that specifically predict meaningful benefit with vitamin D supplementation; overall certainty of evidence very low
The Endocrine Society no longer endorses its previous definitions of vitamin D "sufficiency" (at least 30 ng/mL [75 nmol/L]) or "insufficiency" (greater than 20 ng/mL [50 nmol/L] but lower than 30 ng/mL [75 nmol/L])
Original publication
Vitamin D Insufficiency and Epistemic Humility: An Endocrine Society Guideline Communication. J Clin Endocrinol Metab. Published 3 June 2024. doi:10.
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