Association between socioeconomic deprivation and bone health status in the United Kingdom (UK) biobank cohort participants
Authors' conclusion
Socioeconomic deprivation was significantly associated with poor bone health and falls.
Study context
- Population
- UK Biobank cohort participants aged 40–69 years at recruitment during 2006–2010
- Participants
- 502,682 participants
- Exposure
- Most deprived vs least deprived quantile
- Outcome
- Four outcomes: low BMD/osteopenia, fall in last year, fracture in last five years, fracture from a simple fall in last five years
Methodological detailsbaseline measures from UK Biobank cohort, multivariable logistic regression
- Baseline measures from UK Biobank cohort
- Multivariable logistic regression
Main finding
As reported in the abstract
Fall, fracture, fracture from simple fall and osteopenia (adjusted odds)
Each group vs least deprivedEstimate (95% CI)
Most deprived
OR (fall) 1.46(1.42–1.49)
Most deprived
OR (fracture in last five years) 1.26(1.22–1.30)
Most deprived
OR (fracture from simple fall) 1.31(1.26–1.36)
Most deprived
OR (osteopenia) 1.16(1.13–1.19)
Observational data: associations, not effects.
Further findings
Baseline prevalence (all participants)
- Low bone density (heel T-score < −1 SD)
- 29%
- Fall in the previous year
- 20%
- Fracture in the previous five years
- 10%
- Simple fall as cause, among those with fracture
- 60%
Original publication
Association between socioeconomic deprivation and bone health status in the UK biobank cohort participants. Osteoporos Int. Published 28 May 2024. doi:10.
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