Osteoporosis, bone & mineral

Diagnostic performance of radiomics for predicting osteoporosis in adults: a systematic review and meta-analysis

Osteoporos IntPublished Systematic review and meta-analysis of diagnostic accuracy studies

Authors' conclusion

The results supported that the radiomic techniques had good accuracy in diagnosing osteoporosis or abnormal bone mass.

Study context

Population
Adults; studies applying radiomics to diagnosing osteoporosis or abnormal bone mass (PubMed, EMBASE, Web of Science, Cochrane Library, inception to June 1, 2023)
Participants
5,926 adults10 retrospective studies
Outcome
Diagnostic accuracy of radiomics for predicting osteoporosis
Methodological detailsbivariate random effects model, meta-regression, radiomics quality score (RQS), METhodological RadiomICs Score (METRICS) and QUADAS-2 quality assessment
  • Bivariate random effects model
  • Meta-regression
  • RQS, METRICS and QUADAS-2 quality assessment

Pooled result

As reported in the abstract

Pooled diagnostic accuracy of radiomics for osteoporosis or abnormal bone mass

Pooled diagnostic OR (bivariate random effects model)

57.22

95% CI 27.62–118.52

Pooled sensitivity

87%

95% CI 81–92%

Pooled specificity

87%

95% CI 77–93%

Summary ROC AUC of radiomic models

0.94

range 0.8 to 0.98

Further pooled results

Study quality: METRICS score

Mean METRICS score
70.1% (range 49.6-83.2%)

Original publication

Diagnostic performance of radiomics for predicting osteoporosis in adults: a systematic review and meta-analysis. Osteoporos Int. Published 27 May 2024. doi:10.1007/s00198-024-07136-y

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