Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline

Suggests empiric vitamin D supplementation for children and adolescents aged 1 to 18 years to prevent nutritional rickets and for its potential to lower the risk of respiratory tract infections

Suggests empiric vitamin D supplementation for those aged 75 years and older for its potential to lower the risk of mortality

Suggests empiric vitamin D supplementation in pregnancy for its potential to lower the risk of preeclampsia, intra-uterine mortality, preterm birth, SGA birth and neonatal mortality

Suggests empiric vitamin D supplementation for those with high-risk prediabetes for its potential to reduce progression to diabetes

For nonpregnant people older than 50 years for whom vitamin D is indicated, suggests daily vitamin D rather than intermittent high doses

Suggests against empiric vitamin D supplementation above the current Dietary Reference Intakes (DRI) to lower the risk of disease in healthy adults younger than 75 years

Suggests against routine 25(OH)D testing in all populations considered