Type 2 & other diabetes

Vegetable, but Not Potato, Intake Is Associated With a Lower Risk of Type 2 Diabetes in the Danish Diet, Cancer and Health Cohort

Diabetes CarePublished Prospective cohort study

Main finding · Incident T2D, total vegetable intakeResult — go to the resultLower risk 21% 95% CI 16–26%

Authors' conclusion

The findings provide evidence that a higher vegetable, but not potato, intake might help mitigate T2D risk, partly by reducing BMI.

Study context

Population
Participants of the Danish Diet, Cancer and Health cohort7,695 T2D cases
Participants
54,793 participants
Exposure
Highest vs lowest quintile of total vegetable intake
Outcome
Incident T2D
Follow-up
Median 16.3 years
Methodological detailsmultivariable-adjusted Cox proportional hazards models, mediation analysis (natural direct and indirect effects)
  • Multivariable-adjusted Cox proportional hazards models
  • Mediation analysis (natural direct and indirect effects)

Main finding

Incident T2D, total vegetable intake

Lower risk

21%

95% CI 16–26%

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeHigher risk (95% CI)
Incident T2D, potato intake (highest median 256 vs lowest median 52 g/day)Higher risk with highest quintile; multivariable-adjusted9% (2–16%)
OutcomeDifference (kg/m²) (95% CI)
Baseline BMI, total vegetable intake (cross-sectional)Lower BMI with highest quintile; multivariable-adjusted0.35 (−0.46 to −0.24)

Mediation by baseline BMI of vegetable–T2D association

Proportion mediated by baseline BMI
∼21%

Incident T2D, potato intake (highest median 256 vs lowest median 52 g/day)

No association after accounting for underlying dietary pattern

Incident T2D, vegetable subclasses

Higher intake of green leafy and cruciferous vegetables associated with statistically significantly lower T2D risk

Original publication

Vegetable, but Not Potato, Intake Is Associated With a Lower Risk of Type 2 Diabetes in the Danish Diet, Cancer and Health Cohort. Diabetes Care. Published 5 December 2022. doi:10.2337/dc22-0974

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