Understanding the pathways between prenatal and postnatal factors and overweight outcomes in early childhood: a pooled analysis of seven cohorts
Authors' conclusion
Maternal pre-pregnancy BMI, infant birth weight, breastfeeding duration and RWG in infancy act in concert to influence early childhood overweight. Future overweight prevention interventions should target RWG in infancy, which showed the strongest association with childhood overweight; and maternal pre-pregnancy BMI, which was implicated in several pathways leading to childhood overweight.
Study context
- Population
- Children from seven Australian and New Zealand cohorts; overweight outcomes at ages 3 to 5 years
- Participants
- 3,572 children7 cohorts
- Outcome
- Child overweight outcomes:
- BMI z-score
- Overweight status
- Follow-up
- Ages 3-5 years
Methodological detailsgeneralized structural equation modelling
- Generalized structural equation modelling
Pooled result
As reported in the abstract
- Maternal pre-pregnancy body mass index (BMI) with infant birth weight: β
- 0.01 (0.01, 0.02) (95% CI)
- Maternal pre-pregnancy BMI with breastfeeding duration ≥6 months: OR
- 0.92 (0.90, 0.93) (95% CI)
- Maternal pre-pregnancy BMI with child BMI z-score: β
- 0.03 (0.03, 0.04) (95% CI)
- Maternal pre-pregnancy BMI with child overweight status: OR
- 1.07 (1.06, 1.09) (95% CI)
- Rapid weight gain (RWG) in infancy with child BMI z-score (strongest direct association): β
- 0.72 (0.65, 0.79) (95% CI)
- RWG in infancy with child overweight status: OR
- 4.49 (3.61, 5.59) (95% CI)
Original publication
Understanding the pathways between prenatal and postnatal factors and overweight outcomes in early childhood: a pooled analysis of seven cohorts. Int J Obes (Lond). Published 3 April 2023. doi:10.
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