Prenatal Bisphenol A Exposure and Sex‐Differentiated Childhood BMI Over Time: A Longitudinal Korean Cohort Study
Authors' conclusion
Prenatal BPA exposure exhibited sexually dimorphic associations with BMI from early childhood to age 10.
Study context
- Population
- Mother-child pairs from a Korean birth cohort; maternal urinary bisphenol A (BPA) measured mid-pregnancy; child BMI and BMI Z-score at ages 2, 4, 6, 8 and 10 years
- Participants
- 528 mother-child pairs
- Exposure
- Prenatal maternal urinary BPA exposure
- Outcome
- Childhood BMI and BMI Z-score
- Follow-up
- Ages 2, 4, 6, 8, and 10 years
Methodological detailslongitudinal, sex-stratified, mixed-effects models
- Longitudinal
- Sex-stratified
- Mixed-effects models
Main finding
As reported in the abstract
Change in BMI per 1-unit increase in log-transformed BPA (mixed-effects models)
| Group | BMI increase | BMI decrease |
|---|---|---|
| Boys | 0.13 kg/m² (95% CI: 0.01, 0.25) | |
| Girls | 0.20 kg/m² (95% CI: −0.32, −0.08) |
BMI increase
Boys0.13 kg/m² (95% CI: 0.01, 0.25)
Girls— not stated in the abstract
BMI decrease
Boys— not stated in the abstract
Girls0.20 kg/m² (95% CI: −0.32, −0.08)
Observational data: associations, not effects.
Further findings
BMI Z-score
- Similar patterns were observed for BMI Z-score
Maternal BPA concentration · mid-pregnancy
- Mean maternal BPA concentration
- 2.3 μg/g creatinine
Original publication
Prenatal Bisphenol A Exposure and Sex‐Differentiated Childhood BMI Over Time: A Longitudinal Korean Cohort Study. Pediatr Obes. Published 5 July 2026. doi:10.
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