Thyroid disease

Ultrasound features and risk stratification system in NIFT-P and other follicular-patterned thyroid tumors

Eur J EndocrinolPublished Retrospective cohort study

Authors' conclusion

Ultrasound features of NIFT-P are frequently superimposable to those of nodules with low suspicion of malignancy. The NIFT-P is almost never classified in the high-suspicious category according to the main US RSS. Therefore, although the preoperative identification of NIFT-P remains a challenge, neck US can be integrated in the algorithm of management of nodules with indeterminate cytology, suggesting a possible conservative approach in those with low-suspicious features.

Study context

Population
Consecutive patients undergoing thyroid surgery with ≥1 nodule histologically NIFT-P, follicular variant of PTC (FV-PTC), follicular thyroid carcinoma (FTC) or follicular adenoma (FA)403 patients
Participants
116 / 170 / 76 / 90
Exposure
Ultrasound (US) features and US risk stratification systems in NIFT-P vs other follicular-patterned thyroid tumours (FV-PTC, FTC, FA)
  • NIFT-Pn = 116reference
  • FV-PTCn = 170
  • FTCn = 76
  • FAn = 90
Outcome
US features and US RSS classification
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

Indeterminate cytology

77%

Observational data: associations, not effects.

Original publication

Ultrasound features and risk stratification system in NIFT-P and other follicular-patterned thyroid tumors. Eur J Endocrinol. Published 2 August 2023. doi:10.1093/ejendo/lvad095

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