Trends and Disparities in Diabetes Mellitus and Atrial fibrillation Related Mortality in the United States: 1999–2020
Authors' conclusion
Rising DM and AF-related deaths highlight a growing burden, particularly in men, NH American Indian/Alaskan Natives and Whites, and rural populations
Study context
- Population
- US adults aged ≥25 years with comorbid diabetes mellitus (DM) and atrial fibrillation (AF)-related deaths, 1999–2020
- Participants
- 419,036 deaths
- Outcome
- DM and AF related AAMR per 100,000 and APC
- Follow-up
- 1999 to 2020
Methodological detailsCDC WONDER database, age-adjusted mortality rates and annual percent change
- CDC WONDER database
- Age-adjusted mortality rates and annual percent change
Main finding
As reported in the abstract
AAMR per 100,000
AAMR in 1999
4.83
AAMR in 2020
15.91
Annual percent change (APC) 2018 to 2020
15.01
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| AAMR by sex | Men 11.23 · Women 7.16 |
| AAMR by race/ethnicity | NH American Indian/Alaskan Natives 9.54 · NH Whites 9.16 · NH Asian/Pacific Islanders 6.04 |
| AAMR by urbanization | Non-metropolitan 10.32 · Metropolitan 8.53 |
| AAMR by regionHighest regional AAMR | Western U.S. 9.87 |
- AAMR by race/ethnicity: highest: NH American Indian/Alaskan Natives and Whites; lowest: NH Asian/Pacific Islanders
AAMR by age
- Older adults (≥65) had higher age-adjusted mortality rates (AAMRs) than younger adults (25-64)
Original publication
Trends and Disparities in Diabetes Mellitus and Atrial fibrillation Related Mortality in the United States: 1999–2020. Diabetes Res Clin Pract. Published 19 March 2025. doi:10. 1016/ j. diabres. 2025. 112112
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