Type 2 & other diabetes

Cardiovascular mortality trends and disparities among older adults (≥65 years) with type 2 diabetes in the United States: a CDC WONDER database analysis, 1999–2023

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

Cardiovascular mortality among older adults with type 2 diabetes increased over 25 years, with a devastating acceleration during 2019-2021 that temporally coincided with the COVID-19 pandemic. Persistent sex-, racial-, and geographic-based disparities, combined with evolving cardiovascular mortality patterns, underscore the imperative for targeted interventions addressing the fundamental social determinants of health underlying these inequities.

Study context

Population
US adults ≥65 years with T2D, cardiovascular deaths with T2D as contributing cause, stratified by sex, age group, race/ethnicity and region
Participants
529,472 cardiovascular deaths
Outcome
Age-adjusted mortality rates (AAMR) for cardiovascular deaths with T2D as a contributing cause
Follow-up
1999–2023
Methodological detailsCDC WONDER database analysis, 25-year trends 1999–2023
  • CDC WONDER database analysis
  • 25-year trends 1999–2023

Main finding

As reported in the abstract

Cardiovascular AAMR · 1999 to 2023

Mortality increase during 2019–2021, coinciding with the COVID-19 pandemic

26.2%

Observational data: associations, not effects.

Further findings

Age-adjusted mortality rates (AAMR) by sex

Men consistently had higher AAMR and steeper increases

AAMR by race/ethnicity · 2023

Hispanic older adults shifted from third-highest to highest AAMR by 2023

AAMR by geography

States with elevated mortality concentrated in West and Midwest

Causes of cardiovascular death

AF emerged as 5th leading cause; increase in AAMR
624.7%
Atherosclerotic heart disease remained the leading cause

Original publication

Cardiovascular mortality trends and disparities among older adults (≥65 years) with type 2 diabetes in the United States: a CDC WONDER database analysis, 1999–2023. Diabetes Res Clin Pract. Published 14 January 2026. doi:10.1016/j.diabres.2026.113107

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.