Thyroid disease

Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020

J Clin Endocrinol MetabPublished Retrospective cohort study

Authors' conclusion

TSH testing rates among commercially insured individuals without known thyroid disease appears stable over time, with higher frequency in females and with increasing age.

Study context

Population
Adults 18–64 years old without evidence of thyroid disease with ≥365 days of continuous enrollment, 2006–2020, IBM MarketScan Claims Database15,138,211 with ≥1 thyroid-stimulating hormone (TSH) test
Participants
67,353,280 adults
Outcome
Trends of TSH tests/1000 eligible patient-months stratified by age, sex and region, and composition of thyroid function testing
Follow-up
2006-2020
Methodological detailsclaims database analysis
  • Claims database analysis

Main finding

As reported in the abstract

TSH testing rates
TSH tests identified
25 606 518
TSH tests/1000 person-months, first study month
11.4
TSH tests/1000 person-months, last study month
11.7
Mean TSH tests/1000 person-months
12.2
TSH testing rate, spring 2020 (sharp drop), tests/1000 person-months
4.2
Females, TSH tests/1000 person-months
16.1
Males, TSH tests/1000 person-months
8.6
Age 18-34 years, TSH tests/1000 person-months
8.2
Age 55-64 years, TSH tests/1000 person-months
15.4
Thyroid function testing episodes including only TSH
70.8%

Observational data: associations, not effects.

Further findings

Characteristics of patients contributing a TSH testing episode

Aged 45-54 years
29.8%
Female
63.6%

Original publication

Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020. J Clin Endocrinol Metab. Published 27 October 2023. doi:10.1210/clinem/dgad632

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