Trends in all-cause and cause-specific mortality in older adults with and without diabetes: A territory-wide analysis in one million older adults in Hong Kong
Authors' conclusion
Mortality continued to decline in older adults with and without diabetes, mainly driven by a decline in CVD deaths, with no narrowing of the mortality gap. Our findings call for continued actions to address excess mortalities especially in older men with diabetes and younger older adults.
Study context
- Population
- Older adults aged ≥65 years with ≥1 attendance in the Hong Kong Hospital Authority in 2014–2018; 31.7 % with diabetes
- Participants
- 1,142,000 adults
- Exposure
- Older adults with diabetes vs without diabetes
- Outcome
- Trends in age- and sex-standardised all-cause and cause-specific (CVD, cancer, non-CVD and non-cancer) mortality
- Follow-up
- 2014-2018
Methodological detailsterritory-wide, Joinpoint regression, age- and sex-standardised
- Territory-wide
- Joinpoint regression
- Age- and sex-standardised
Main finding
As reported in the abstract
All-cause mortality trend (AAPC)
With diabetes
−1.6
AAPC · 95% CI −2.7–-0.4
Without diabetes
−3.1
AAPC · CI −4.2–-2.1
Observational data: associations, not effects.
Further findings
AAPC
| Outcome | With diabetes | Without diabetes |
|---|---|---|
| CVD-cause mortality trend (AAPC) | −5.5 (CI −6.8–-4.1) | −5.8 (CI −8.6–-2.9) |
CVD-cause mortality trend (AAPC)
- Largest declines were seen for CVD-cause mortality
Cancer-cause mortality
- Similar in both groups with no change
Men with diabetes
- Men with diabetes showed less favourable improvements
Age group 65-69
- Increasing mortality trend only in the 65-69 age-group regardless of diabetes status
Original publication
Trends in all-cause and cause-specific mortality in older adults with and without diabetes: A territory-wide analysis in one million older adults in Hong Kong. Diabetes Res Clin Pract. Published 14 March 2024. doi:10.
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