Tracking correlations and predictors of plasma glucose in young adulthood: A comprehensive analysis from adolescence to young adulthood in TLGS study
Authors' conclusion
Tracking correlation was observed for FPG, suggesting that monitoring and managing risk factors in adolescence may have implications for future glucose metabolism in young adulthood.
Study context
- Population
- Participants of the Tehran lipid and glucose study aged 11–18 (adolescence) and 19–40 years (adulthood), 1999–20181,033 male
- Participants
- 2,188 participants
- Outcome
- Tracking correlations of FPG in adolescence with FPG and 2 h-PG in adulthood; predictors of young-adult FPG and 2 h-PG
Methodological detailsgrowth curve models, linear regression
- Growth curve models
- Linear regression
Main finding
As reported in the abstract
Tracking correlations (AUCs from growth curve models)
Partial correlation between AUCs of fasting plasma glucose (FPG) in adolescence and adulthood
0.37
P < 0.001
Correlation between AUCs of FPG in adolescence and 2 h-PG in adulthood
0.17
P < 0.001
Observational data: associations, not effects.
Further findings
- AUC of FPG was a significant positive predictor for both FPG and 2 h-PG in young adulthood
- Other predictors of adult FPG: sex, and BMI and TG/HDL-C ratio during both adolescence and adulthood
Original publication
Tracking correlations and predictors of plasma glucose in young adulthood: A comprehensive analysis from adolescence to young adulthood in TLGS study. Diabetes Res Clin Pract. Published 20 March 2024. doi:10.
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