Diabetes technology

Time Spent in Hypoglycemia According to Age and Time of Day: Observations During Closed-Loop Insulin Delivery

Diabetes Technol TherPublished Retrospective analysis of hybrid closed-loop studies

Authors' conclusion

Time in hypoglycemia was highest in the pediatric age group during closed-loop insulin delivery. Hypoglycemia burden was lowest overnight across all age groups.

Study context

Population
People with T1D using hybrid closed-loop insulin delivery
Participants
88 people
Exposure
Time in hypoglycemia by age group and time of day during closed-loop insulin delivery
Outcome
Time spent in hypoglycemia <3.9 mmol/L (<70 mg/dL)
Follow-up
8 weeks of data
Methodological detailspooled data from hybrid closed-loop studies
  • Pooled data from hybrid closed-loop studies

Main finding

As reported in the abstract

Time in hypoglycemia <3.9 mmol/L (<70 mg/dL), 24-h period
  • Between Young children (2-7 years) and Older adults (≥60 years): P < 0.001 for difference between age groups

Observational data: associations, not effects.

Further findings

Time in hypoglycemia: nighttime (midnight-05:59) vs daytime (06:00-23:59)

Lower during nighttime than daytime across all age groups

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Time Spent in Hypoglycemia According to Age and Time of Day: Observations During Closed-Loop Insulin Delivery. Diabetes Technol Ther. Published 13 June 2023. doi:10.1089/dia.2023.0061

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