Gestational diabetes & diabetes in pregnancy
Third-Trimester Energy-Restriction or Weight Loss and Maternal and Child Body Composition One Year Postnatally After a Pregnancy With Gestational Diabetes: Results From the DiGest Follow-up Study
Authors' conclusion
Among women with gestational diabetes and high BMI, energy restriction or weight loss in pregnancy were associated with no adverse effects on offspring weight or growth in the first year.
Study context
- Population
- Women with GDM and BMI ≥25 kg/m², follow-up to 12 months postnatally
- Comparison
- Reduced-energy (1,200 kcal/day) vs standard-energy (2,000 kcal/day) diet in the third trimester; and pregnancy weight loss vs no weight loss (cohort analysis)
- Primary endpoint
- Maternal and offspring weight postnatally
- Follow-up
- Up to 12 months postnatally
Methodological detailstrial and cohort analyses, adjusted linear and logistic regression, Super-Imposition by Translation and Rotation model
- Trial and cohort analyses
- Adjusted linear and logistic regression
- Super-Imposition by Translation and Rotation model
Primary result
As reported in the abstract
Antenatal and postnatal growth by randomised allocation · first year of life
- Allocation to energy restriction did not alter antenatal or postnatal growth; infants in both groups had normal weight for age throughout the first year
- Trial analysis
Further findings
Maternal weight in women who lost weight in pregnancy (cohort analysis) · 3 and 12 months
- Average pregnancy weight loss
- 3 kg
- Lower adjusted maternal weight at 3 but not 12 months
- Cohort analysis
Infant outcomes after exposure to pregnancy weight loss (cohort analysis)
- Lower risk of large-for-gestational age at birth
- Lower fat mass at 3 months
- No evidence of growth faltering or excessive catch-up or catch-down growth
- Cohort analysis
Safety
Low infant weight after exposure to pregnancy weight loss
- No higher prevalence of low infant weight; weight for age < −2 SD
- <5%
- Cohort analysis
Original publication
Third-Trimester Energy-Restriction or Weight Loss and Maternal and Child Body Composition One Year Postnatally After a Pregnancy With Gestational Diabetes: Results From the DiGest Follow-up Study. Diabetes Care. Published 27 August 2026. doi:10. 2337/ dc26-0405
Composed by AI from the published abstract and checked against it. How Briefs are made →