Gestational diabetes & diabetes in pregnancy

Energy Restriction, Weight Loss, Glycemia, and Breastfeeding Outcomes in Gestational Diabetes: A DiGest Trial Secondary Analysis

Diabetes CarePublished Secondary analysis of the DiGest randomised controlled trial

Authors' conclusion

Improved late pregnancy glycemia and decreased glucose variability, but not weight loss or energy restriction, were associated with breastfeeding after gestational diabetes.

Study context

Population
Pregnant women with GDM in the DiGest RCT304 with breastfeeding data
Participants
425 women
Comparison
Reduced-energy vs standard-energy diet box from 29 weeks until delivery
Primary endpoint
Breastfeeding outcomes
Methodological detailsmasked CGM
  • Masked CGM

Primary result

As reported in the abstract

  • Energy restriction in late pregnancy did not affect breastfeeding outcomes
  • ≥90% TIR (3.5-6.7 mmol/L; 63-120 mg/dL) with low glycemic variability (CV and SD), but not weight loss, associated with any breastfeeding at 3 months postnatally

Original publication

Energy Restriction, Weight Loss, Glycemia, and Breastfeeding Outcomes in Gestational Diabetes: A DiGest Trial Secondary Analysis. Diabetes Care. Published 17 April 2025. doi:10.2337/dc24-2625

Composed by AI from the published abstract and checked against it. How Briefs are made →

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